Sesamin protects SH-SY5Y cells against mechanical stretch injury and promoting cell survival
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Acteoside protects human neuroblastoma SH-SY5Y cells against beta-amyloid-induced cell injury.
Amyloid beta-peptide (Abeta) has been implicated in the pathogenesis of AD. It can cause cell death in AD by evoking a cascade of oxidative damage to neurons. So antioxidant compounds may throw a light on the treatment of AD. In the present study, we investigated the protective effect of acteoside (AS), an antioxidative phenylethanoid glycoside, on Abeta(25-35)-induced SH-SY5Y cell injury. Expo...
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Baicalin, an extract from the dried root of Scutellaria baicalensis Georgi, was shown to be neuroprotective. However, the precise mechanisms are incompletely known. In this study, we determined the effect of baicalin on thrombin induced cell injury in SH-SY5Y cells, and explored the possible mechanisms. SH-SY5Y cells was treated with thrombin alone or pre-treated with baicalin (5, 10, 20 μM) fo...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2017
ISSN: 1471-2202
DOI: 10.1186/s12868-017-0378-8